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Writer's pictureShravani Kulkarni

BENZALKONIUM CHLORIDE(DETTOL)


benzalkonium chloride

Category - Antiseptic


INTRODUCTION:


It is an antiseptic. It is diagnosed earlier to surgical procedures or for minor wound care to decrease risks of infection. It can be applied to treat cold sores. As a quaternary ammonium compound, benzoalkonium chloride is the most widely used antibacterial preservative. It was initially used in hard contact lens solutions but is now ubiquitous. It is currently present in the majority of topical multipurpose eye treatments. If you have any queries you can take guidance from your nearest physician. It is also used as active ingredient in products like antibacterial, antiseptic, or disinfectant soaps, topical sanitizers, or cleaning agents.

Uses:


benzalkonium chloride uses

How to apply:

  1. This medication is used for only skin. Keep out of your mouth, ears, eyes may burn and nose.

  2. Wash your hands before and after use.

  3. If medication is applied for skin then don't wash your hands.

  4. Put on the affected part before use. Make sure to dry well.

  5. If there is wound treatment then clean the affected area and sterilize it with gauze.

  6. Take the medication as soon as possible in case you miss the dose.

Storage conditions:

The medication should be stored in cool and purifying air.

Side effects:


There is rare cases of side effects

1. Any symptoms of infections

2. Redness

3. Swelling

4. Very bad skin irritation

If you have any of these symptoms consult your nearest doctor.


benzalkonium chloride swelling


Drug mechanism:


Pharmacodynamics:


Benzalkonium chloride solutions are effective against bacteria, some viruses, fungi, and protozoa, but may not be effective against bacterial spores. Compared to Gram-negative bacteria, they are less effective against Gram-positive bacteria. The concentration of the solution determines whether it is bacteriostatic or bactericidal. The drug's activity is not affected by pH but increases with higher temperatures and longer exposure times

Pharmacokinetics:


Benzalkonium chloride intermolecular interactions, leading to impaired control of cell permeability and leakage of cellular contents. It can also inactivate enzymes that control respiration and metabolic activity in cells, disrupting biochemical systems and rendering bacteria unable to function normally. Benzalkonium chloride is a topical antibacterial, antiseptic, or disinfectant that is poorly absorbed, making it effective in its current level of use and unlikely to be significantly absorbed beyond that.

Safety measures:


benzalkonium chloride safety measures

Allergic reactions:


1.Itching

2.Swollen

3.Blistered

4.Peeling skin

5.Wheezing skin

6.Tightness in the chest

7.Trouble breathing

8.Swelling of mouth, nose, ears and eyes.

benzalkonium chloride allergies


Consult your physician and diagnose as per their guidance


When to see doctor:


If you notice any kind of irritation swelling, rashes then

1.Stop using product

2.Consult your physician

3.Let you doctor know if you have any type of disease

Available dosage forms:


Spray- topical solution

Strength - 0.13%

Pediatric topical usage

Benzalkonium chloride-pramoxine topical 0.13%-1% spray:

2 years or older: Clean affected area then spray a small amount 1 to 3 times daily. May cover with a sterile bandage after the spray has dried.

Adult Topical usage:


Tincture of benzalkonium chloride is used for the disinfection of unbroken skin or treatment of superficial injuries.

Benzalkonium chloride-pramoxine.

Important note:


●Used before surgery or to treat minor injuries to reduce the risk of infection.

●Hand sanitizers containing BACs typically contain BACs at concentrations between 0.1% and 0.13%. BACs are typically dissolved in water and/or alcohol solutions along with other ingredients such as moisturizers and fragrances to create hand sanitizing gels or sprays.

●It is important to note that although BAC-based hand sanitizers are effective in reducing the spread of infection, they should not be used as the sole means of preventing infection.

Various brands:





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